Difference between revisions of "Endocrine disrupting compounds"

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Definition|title=Endocrine Disrupting Compounds (EDCs)
 
Definition|title=Endocrine Disrupting Compounds (EDCs)
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==Notes==
 
==Notes==
  
Endocrine systems are found in most varieties of animal life. The endocrine system is made up of glands, which secrete hormones, and receptor cells which detect and react to the hormones. Hormones are released by glands and travel throughout the body, acting as chemical messengers. Hormones interface with cells that contain matching receptors in or on their surfaces. The hormone binds with the receptor, much like a key would fit into a lock.
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Endocrine systems are found in all vertebrate and most invertebrate animal species. The [[endocrine system]] is made up of glands which secrete hormones to body fluids, and receptor cells which detect and react to the hormones. The hormones act as chemical messengers. Hormones bind to cells that contain matching receptors in or on their surfaces, much like a key would fit into a lock.
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Disruption of the endocrine system can occur in various ways. Some chemicals mimic a natural hormone, fooling the body into over-responding to the stimulus, or responding at inappropriate times. Other endocrine disruptors block the receptor site on a cell. Still others directly stimulate or inhibit the endocrine system and cause overproduction or underproduction of hormones. The substances that show these effects are known as Endocrine Disrupting Chemicals (EDCs) or Hormone Disrupting Chemicals (HDCs).
  
Disruption of the endocrine system can occur in various ways. Some chemicals mimic a natural hormone, fooling the body into over-responding to the stimulus, or responding at inappropriate times. Other endocrine disruptors block the effects of a hormone from certain receptors by blocking the receptor site on a cell. Still others directly stimulate or inhibit the endocrine system and cause overproduction or underproduction of hormones. Medical interventions commonly manipulate the endocrine system for the betterment of a patient, and side effects of such therapy can be interpreted as due to endocrine disruption. Substances in question are also known as Endocrine Disrupting Chemicals (EDCs) or Hormone Disrupting Chemicals (HDCs), and belong to the group of xenobiotics, foreign chemicals that affect a biological system.
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The most conspicuous EDCs are those that affect reproduction. EDCs have been demonstrated to markedly affect animal populations in the coastal environment.
  
 
==References==
 
==References==
 
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==See also==
 
==See also==
[[Types of pollutants]] <br>
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:[[Portal:Ecotox|Coastal Wiki articles related to ecotoxicology]]
[[Endocrine disrupting compounds in the coastal environment]] <br>
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[[TBT and Imposex]]
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[[Category:Coastal and marine pollution]]

Revision as of 20:14, 17 February 2019


Definition of Endocrine Disrupting Compounds (EDCs):
Endocrine disruptors are exogenous substances that alter function(s) of the endocrine system and consequently cause adverse health effects in an intact organism, or its progeny, or (sub)populations [1].
This is the common definition for Endocrine Disrupting Compounds (EDCs), other definitions can be discussed in the article

Notes

Endocrine systems are found in all vertebrate and most invertebrate animal species. The endocrine system is made up of glands which secrete hormones to body fluids, and receptor cells which detect and react to the hormones. The hormones act as chemical messengers. Hormones bind to cells that contain matching receptors in or on their surfaces, much like a key would fit into a lock.

Disruption of the endocrine system can occur in various ways. Some chemicals mimic a natural hormone, fooling the body into over-responding to the stimulus, or responding at inappropriate times. Other endocrine disruptors block the receptor site on a cell. Still others directly stimulate or inhibit the endocrine system and cause overproduction or underproduction of hormones. The substances that show these effects are known as Endocrine Disrupting Chemicals (EDCs) or Hormone Disrupting Chemicals (HDCs).

The most conspicuous EDCs are those that affect reproduction. EDCs have been demonstrated to markedly affect animal populations in the coastal environment.

References

  1. International Programme on Chemical Safety (IPCS) http://www.who.int/ipcs/en/

See also

Coastal Wiki articles related to ecotoxicology