https://www.coastalwiki.org/w/index.php?title=Marine_Biotechnology_securing_Human_Health&feed=atom&action=history
Marine Biotechnology securing Human Health - Revision history
2024-03-29T12:32:46Z
Revision history for this page on the wiki
MediaWiki 1.31.7
https://www.coastalwiki.org/w/index.php?title=Marine_Biotechnology_securing_Human_Health&diff=60663&oldid=prev
Daphnisd: /* References */
2013-11-07T11:11:18Z
<p><span dir="auto"><span class="autocomment">References</span></span></p>
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<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 11:11, 7 November 2013</td>
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<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><references/></div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><references/></div></td></tr>
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Daphnisd
https://www.coastalwiki.org/w/index.php?title=Marine_Biotechnology_securing_Human_Health&diff=56748&oldid=prev
Daphnisd at 12:26, 8 March 2013
2013-03-08T12:26:06Z
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<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 12:26, 8 March 2013</td>
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<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* Improve the technical aspects of the biodiscovery pipeline, including the separation of bioactives, bio-assays that can accommodate diverse material from marine sources, dereplication strategies and structure determination methods and software;</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* Improve the technical aspects of the biodiscovery pipeline, including the separation of bioactives, bio-assays that can accommodate diverse material from marine sources, dereplication strategies and structure determination methods and software;</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* Overcome the supply problem to provide a sustainable source of novel pharmaceutical and healthcare products through scientific advances in the fields of aquaculture, microbial and tissue culture, chemical synthesis and biosynthetic engineering.</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* Overcome the supply problem to provide a sustainable source of novel pharmaceutical and healthcare products through scientific advances in the fields of aquaculture, microbial and tissue culture, chemical synthesis and biosynthetic engineering.</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr>
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Daphnisd
https://www.coastalwiki.org/w/index.php?title=Marine_Biotechnology_securing_Human_Health&diff=56747&oldid=prev
Daphnisd at 12:25, 8 March 2013
2013-03-08T12:25:12Z
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<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 12:25, 8 March 2013</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1" >Line 1:</td>
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<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>In recent years, the chemistry of natural products derived from marine organisms has become the focus of a much greater research effort. Currently there are several products already on the market and around 15 marine natural products in various phases of clinical development, mainly in the oncology area, with more on the way. Nevertheless, the seas and oceans represent a huge potential source of new drugs, innovative treatments and diagnostic tools for human and animal health.  </div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>In recent years, the chemistry of natural products derived from marine organisms has become the focus of a much greater research effort. Currently there are several products already on the market and around 15 marine natural products in various phases of clinical development, mainly in the oncology area, with more on the way. Nevertheless, the seas and oceans represent a huge potential source of new drugs, innovative treatments and diagnostic tools for human and animal health.  </div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>{|<del class="diffchange diffchange-inline">align="right" width="300px" </del>margin style="text-align:center; font-size:85%; margin-left: 1em"</div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>{|margin style="<ins class="diffchange diffchange-inline">float: right; </ins>text-align:center; font-size:85%; margin-left: 1em<ins class="diffchange diffchange-inline">;width:400px</ins>"</div></td></tr>
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Daphnisd
https://www.coastalwiki.org/w/index.php?title=Marine_Biotechnology_securing_Human_Health&diff=54622&oldid=prev
Angelm at 14:31, 13 November 2012
2012-11-13T14:31:53Z
<p></p>
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<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 14:31, 13 November 2012</td>
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<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>==<del class="diffchange diffchange-inline">Recommendations </del>to <del class="diffchange diffchange-inline">improve </del>biodiscovery of novel <del class="diffchange diffchange-inline">marine-derived biomolecules </del>and the <del class="diffchange diffchange-inline">development </del>of <del class="diffchange diffchange-inline">new tools </del>and <del class="diffchange diffchange-inline">approaches for drug development==</del></div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>==<ins class="diffchange diffchange-inline">Research priorities and objectives ==</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">'''Overarching research target:''' </ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">Development of novel drugs, treatments and health and personal care products.</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">'''Key research priorities:''' </ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">* Increase the focus on the basic research (taxonomy, systematics, physiology, molecular genetics and (chemical) ecology of marine species and organisms from unusual and extreme environments </ins>to <ins class="diffchange diffchange-inline">increase chances of success in finding novel bioactives;</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">* Improve the technical aspects of the </ins>biodiscovery <ins class="diffchange diffchange-inline">pipeline, including the separation of bioactives, bio-assays that can accommodate diverse material from marine sources, dereplication strategies and structure determination methods and software;</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">* Overcome the supply problem to provide a sustainable source </ins>of novel <ins class="diffchange diffchange-inline">pharmaceutical </ins>and <ins class="diffchange diffchange-inline">healthcare products through scientific advances in </ins>the <ins class="diffchange diffchange-inline">fields </ins>of <ins class="diffchange diffchange-inline">aquaculture, microbial and tissue culture, chemical synthesis </ins>and <ins class="diffchange diffchange-inline">biosynthetic engineering.</ins></div></td></tr>
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Angelm
https://www.coastalwiki.org/w/index.php?title=Marine_Biotechnology_securing_Human_Health&diff=54615&oldid=prev
Angelm at 14:20, 13 November 2012
2012-11-13T14:20:48Z
<p></p>
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<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 14:20, 13 November 2012</td>
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<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'>−</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>==<del class="diffchange diffchange-inline">Case studies showing examples </del>of <del class="diffchange diffchange-inline">progress</del>==</div></td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>==<ins class="diffchange diffchange-inline">Examples </ins>of <ins class="diffchange diffchange-inline">Marine Biotechnology research for Human Health</ins>==</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* [[Marine derived anticancer drugs]]</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* [[Marine derived anticancer drugs]]</div></td></tr>
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Angelm
https://www.coastalwiki.org/w/index.php?title=Marine_Biotechnology_securing_Human_Health&diff=54172&oldid=prev
Fiend: ref
2012-10-01T15:20:58Z
<p>ref</p>
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<td colspan="2" style="background-color: #fff; color: #222; text-align: center;">Revision as of 15:20, 1 October 2012</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1" >Line 1:</td>
<td colspan="2" class="diff-lineno">Line 1:</td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>In recent years, the chemistry of natural products derived from marine organisms has become the focus of a much greater research effort. Currently there are several products already on the market and around 15 marine natural products in various phases of clinical development, mainly in the oncology area, with more on the way. Nevertheless, the seas and oceans represent a huge potential source of new drugs, innovative treatments and diagnostic tools for human and animal health.  </div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>In recent years, the chemistry of natural products derived from marine organisms has become the focus of a much greater research effort. Currently there are several products already on the market and around 15 marine natural products in various phases of clinical development, mainly in the oncology area, with more on the way. Nevertheless, the seas and oceans represent a huge potential source of new drugs, innovative treatments and diagnostic tools for human and animal health.  </div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{|align="right" width="300px" margin style="text-align:center; font-size:85%; margin-left: 1em"</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|[[Image:mbt_health.jpg|400px]]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|-</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|The sponge ''Stylissa massa'' produces an unusual compound palau'amine, with antimicrobial activity. <ref name="Marc Slatter, NOAA-OE">Cayman Islands Twilight Zone 2007</ref> </ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|}</ins></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>The main challenges facing pharmaceutical discovery from marine bioresources are linked to: legal aspects (secure access to marine resources and intellectual property rights); quality of marine resources (identification and variability); technology (screening of active compounds and replication, preventing repeated rediscovery); and structural costs of drug discovery from natural products.</div></td><td class='diff-marker'> </td><td style="background-color: #f8f9fa; color: #222; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>The main challenges facing pharmaceutical discovery from marine bioresources are linked to: legal aspects (secure access to marine resources and intellectual property rights); quality of marine resources (identification and variability); technology (screening of active compounds and replication, preventing repeated rediscovery); and structural costs of drug discovery from natural products.</div></td></tr>
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https://www.coastalwiki.org/w/index.php?title=Marine_Biotechnology_securing_Human_Health&diff=54169&oldid=prev
Fiend: New page: In recent years, the chemistry of natural products derived from marine organisms has become the focus of a much greater research effort. Currently there are several products already on the...
2012-10-01T14:49:25Z
<p>New page: In recent years, the chemistry of natural products derived from marine organisms has become the focus of a much greater research effort. Currently there are several products already on the...</p>
<p><b>New page</b></p><div>In recent years, the chemistry of natural products derived from marine organisms has become the focus of a much greater research effort. Currently there are several products already on the market and around 15 marine natural products in various phases of clinical development, mainly in the oncology area, with more on the way. Nevertheless, the seas and oceans represent a huge potential source of new drugs, innovative treatments and diagnostic tools for human and animal health. <br />
<br />
The main challenges facing pharmaceutical discovery from marine bioresources are linked to: legal aspects (secure access to marine resources and intellectual property rights); quality of marine resources (identification and variability); technology (screening of active compounds and replication, preventing repeated rediscovery); and structural costs of drug discovery from natural products.<br />
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==Case studies showing examples of progress==<br />
<br />
* [[Marine derived anticancer drugs]]<br />
* [[Marine derived painkillers]]<br />
* [[Marine derived antibiotics]]<br />
* [[Marine derived cosmetics]]<br />
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==Recommendations to improve biodiscovery of novel marine-derived biomolecules and the development of new tools and approaches for drug development==</div>
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